The second largest eigenvalue of a graph if it is integral. This statistic is undefined if the second largest eigenvalue of the graph is not integral. Chapter 4 of [1] provides lots of context.

The number of prime nodes in the modular decomposition of a graph.

The number of different graphs obtained from the given graph by removing an edge.

The degree of the minimal polynomial of the largest Laplacian eigenvalue of a graph.

The Grundy number of a graph. The Grundy number $\Gamma(G)$ is defined to be the largest $k$ such that $G$ admits a greedy $k$-coloring. Any order of the vertices of $G$ induces a greedy coloring by assigning to the $i$-th vertex in this order the smallest positive integer such that the partial coloring remains a proper coloring. In particular, we have that $\chi(G) \leq \Gamma(G) \leq \Delta(G) + 1$, where $\chi(G)$ is the chromatic number of $G$ ([[St000098]]), and where $\Delta(G)$ is the maximal degree of a vertex of $G$ ([[St000171]]).

The game chromatic number of a graph. Two players, Alice and Bob, take turns colouring properly any uncolored vertex of the graph. Alice begins. If it is not possible for either player to colour a vertex, then Bob wins. If the graph is completely colored, Alice wins. The game chromatic number is the smallest number of colours such that Alice has a winning strategy.

The tree-depth of a graph. The tree-depth $\operatorname{td}(G)$ of a graph $G$ whose connected components are $G_1,\ldots,G_p$ is recursively defined as $$\operatorname{td}(G)=\begin{cases} 1, & \text{if }|G|=1\\ 1 + \min_{v\in V} \operatorname{td}(G-v), & \text{if } p=1 \text{ and } |G| > 1\\ \max_{i=1}^p \operatorname{td}(G_i), & \text{otherwise} \end{cases}$$ Nešetřil and Ossona de Mendez [2] proved that the tree-depth of a connected graph is equal to its minimum elimination tree height and its centered chromatic number (fewest colors needed for a vertex coloring where every connected induced subgraph has a color that appears exactly once). Tree-depth is strictly greater than [[St000536|pathwidth]]. A [[St001120|longest path]] in $G$ has at least $\operatorname{td}(G)$ vertices [3].

The independence gap of a graph. This is the difference between the independence number [[St000093]] and the minimal size of a maximally independent set of a graph. In particular, this statistic is $0$ for well covered graphs

The cardinality of a minimal cycle-isolating set of a graph. Let $\mathcal F$ be a set of graphs. A set of vertices $S$ is $\mathcal F$-isolating, if the subgraph induced by the vertices in the complement of the closed neighbourhood of $S$ does not contain any graph in $\mathcal F$. This statistic returns the cardinality of the smallest isolating set when $\mathcal F$ contains all cycles.

The rank-width of a graph.