The determinant of the distance matrix of a connected graph.

The number of induced subgraphs. A subgraph $H \subseteq G$ is induced if $E(H)$ consists of all edges in $E(G)$ that connect the vertices of $H$.

The largest Laplacian eigenvalue of a graph if it is integral. This statistic is undefined if the largest Laplacian eigenvalue of the graph is not integral. Various results are collected in Section 3.9 of [1]

The energy of a graph, if it is integral. The energy of a graph is the sum of the absolute values of its eigenvalues. This statistic is only defined for graphs with integral energy. It is known, that the energy is never an odd integer [2]. In fact, it is never the square root of an odd integer [3]. The energy of a graph is the sum of the energies of the connected components of a graph. The energy of the complete graph $K_n$ equals $2n-2$. For this reason, we do not define the energy of the empty graph.

The Colin de Verdière graph invariant.

The number of minimal elements in a poset.

The competition number of a graph. The competition graph of a digraph $D$ is a (simple undirected) graph which has the same vertex set as $D$ and has an edge between $x$ and $y$ if and only if there exists a vertex $v$ in $D$ such that $(x, v)$ and $(y, v)$ are arcs of $D$. For any graph, $G$ together with sufficiently many isolated vertices is the competition graph of some acyclic digraph. The competition number $k(G)$ is the smallest number of such isolated vertices.

The hat guessing number of a graph. Suppose that each vertex of a graph corresponds to a player, wearing a hat whose color is arbitrarily chosen from a set of $q$ possible colors. Each player can see the hat colors of his neighbors, but not his own hat color. All of the players are asked to guess their own hat colors simultaneously, according to a predetermined guessing strategy and the hat colors they see, where no communication between them is allowed. The hat guessing number $HG(G)$ of a graph $G$ is the largest integer $q$ such that there exists a guessing strategy guaranteeing at least one correct guess for any hat assignment of $q$ possible colors. Because it suffices that a single player guesses correctly, the hat guessing number of a graph is the maximum of the hat guessing numbers of its connected components.

The Frankl number of a lattice. For a lattice $L$ on at least two elements, this is $$ \max_x(|L|-2|[x, 1]|), $$ where we maximize over all join irreducible elements and $[x, 1]$ denotes the interval from $x$ to the top element. Frankl's conjecture asserts that this number is non-negative, and zero if and only if $L$ is a Boolean lattice.